Staff Scientist - Precision Oncology of Gastrointestinal Cancers Job at City of Hope, Monrovia, CA

  • City of Hope
  • Monrovia, CA

Job Description

DescriptionJoin the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.Led by Dr. Ajay Goel, Professor and Founding Chair of the Department of Molecular Diagnostics and Experimental Therapeutics, our multidisciplinary research group comprises basic researchers, gastroenterologists, surgeons, oncologists, and bioinformaticians, undertaking several collaborative projects involving large international consortia. This position has the potential to become tenure-track upon the receipt of grant funding lasting 3-5 years from a federal agency.Our research focuses on translational studies of the genomic and epigenomic characterization of various gastrointestinal cancers (GI), including colorectal, pancreatic, gastric, esophageal, and hepatocellular cancers. Our group performs cutting-edge research in GI oncology, is very productive, and publishes in high-impact journals such as Nature Cancer, Nature Communications, Nature Biotechnology, Nature Reviews Gastroenterology and Hepatology, New England Journal of Medicine, CA: A Journal for Clinicians, Gastroenterology, Cancer Cell, PNAS, JAMA Oncology, JNCI, Cancer Research, Clinical Cancer Research, , Annals of Surgery, etc.For more information on Dr. Goel’s research, please visit here.If you are passionate about some of the following things, we are working on this may be the perfect opportunity:· Development of cell-free DNA (mutation and methylation), RNA, and exosomal-based liquid assays for early cancer detection, prognosis, and predictive responses to chemotherapies and targeted drugs. · Studying the genetic and epigenetic basis of GI cancers (e.g., aberrant DNA methylation, histone modifications, and non-coding RNAs).· Understanding the biological implications of gut microbiome and its translational application in gastrointestinal cancers· The genetic basis of early-onset colorectal cancer (EO-CRC) and familial/hereditary colorectal cancer. · The role of extracellular vesicles/exosomes in cancer pathogenesis and their role as disease biomarkers.· The role of the tumor microenvironment, stem cells, immune regulation, and identification of novel targeted therapies. · Cancer prevention and adjunctive role of natural and integrative therapy approaches.As a successful candidate, you will be:· Developing liquid biopsy biomarkers for cancer diagnosis, prognosis, and therapy response prediction.· Investigating the epigenetic basis of GI cancers, such as aberrant DNA methylation, histone modifications, and non-coding RNAs.· Exploring the genetics of early-onset and familial/hereditary colorectal cancers.· Studying the tumor microenvironment, stem cells, immune regulation, and identifying targeted therapies.· Investigating extracellular vesicles/exosomes in cancer pathogenesis and as disease biomarkersQualificationsYour qualifications should include:· PhD, MD, or MD/PhD, with a strong background and profound knowledge in the field of oncology, cancer biology, immunology, or immunotherapy.· Prior molecular, cancer biology, and/or translational research experience and evidence of project development and supervision of post-doctoral fellows and technical staff.· Evidence of scientific rigor and excellence as documented by high-impact peer-reviewed publications, as a first/lead author.· Evidence for obtaining successful funding from various foundations or other extramural resources.· Documented evidence of mentoring post-docs, research associates, and others in a research laboratory environment.City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.City of Hope is an equal opportunity employer.To learn more about our Comprehensive Benefits, please CLICK HERE.Job Field: ResearchShift: Days

Job Tags

Work experience placement

Similar Jobs

Gentiva Hospice

Hospice Certified Nursing Assistant - Hospice Aide Job at Gentiva Hospice

 ...Overview Deliver Comfort. Honor Dignity. Transform Care. Are you a Hospice Aide or Certified Nursing Assistant (CNA) who finds purpose in providing compassionate, hands-on care during lifes most meaningful moments? We believe every day is an opportunity to bring... 

The HB Collective

Content Creator Job at The HB Collective

 ...Job Description The HB Collective is looking for reliable, creative, and personable Contract Content Creators to join our growing team. \n \n Creators will work on-site at weddings, events, brand shoots, businesses, and other client projects to capture high-quality... 

Becker's Healthcare

Custom Content Writer & Moderator Job at Becker's Healthcare

 ...Custom Content Writer & Moderator Hybrid Position- Chicago, IL Salary Range $75,000-$95,000 Beckers Healthcare is a multimedia digital and events platform built for healthcares decision-makers. We pair trusted journalism with data-driven intelligence and AI,... 

Permanent Makeup by Thanya LLC

Lash Stylist Job at Permanent Makeup by Thanya LLC

 ...Job Description Job Description Looking for Experienced Lash Stylist Permanent Makeup by Thanya, is looking for lash stylists....  ...-house growth opportunities. We Also Provide: We Pay all Online and Social Media Marketing. We advertise your profile on our... 

National Grid plc

Lead Data Engineer Job at National Grid plc

 ...National Grid is one of the largest investor-owned energy companies in the world, serving communities across Massachusetts, New York, Rhode Island, and the United Kingdom. We are focused on delivering clean, reliable, and affordable energy while supporting the transition...